Scientific and Regulatory Policy Committee

Scientific and Regulatory Policy Committee (SRPC) Review: Interpretation and Use of Cell Proliferation Data in Cancer Risk Assessment.

Increased cell proliferation is a central key event in the mode of action for many non-genotoxic carcinogens, and quantitative cell proliferation data play an important role in the cancer risk assessment of many pharmaceutical and environmental compounds. Currently, there is limited unified information on assay standards, reference values, targeted applications, study design issues, and quality...

sciEntific committEE

Downy mildew is an economically relevant pathogen of cucumbers and other cucurbits caused by the obligate oomycete, Pseudoperonospora cubensis. In recent years, host resistance has been overcome by this pathogen leaving many crops, namely cucumber, vulnerable to this foliar disease. In order to better understand the cucumber-downy mildew interaction at a molecular level, recent efforts have bee...

Scientific and Regulatory Policy Committee (SRPC) paper: validation of digital pathology systems in the regulated nonclinical environment.

Digital Pathology Systems (DPS) are dynamic, image-based computer systems that enable the acquisition, management, and interpretation of pathology information generated from digitized glass slides. This article provides a roadmap for (1) qualification of a whole slide scanner (WSS) during a validation project, (2) validation of software required to generate the whole slide image (WSI), and (3) ...

Scientific committee

s Wednesday, 24 August 2011 22 WWW.PERFORMANCESCIENCE.ORG

Scientific Committee